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Tag: antipsychotics


Bipolar Disorder Drugs May 'Tweak' Genes Affecting Brain

Medications taken by people with bipolar disorder may actually be nudging hundreds of genes that direct the brain to behave more normally, according to new research. 

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AACAP Applauds the AMA on Recommending Further Research & Guidance on the Use of Atypical Antipsychotic Medication


An article from the Psychiatric Times. "How often do the known do the risks of antipsychotics outweigh uncertain clinical benefits? Before jumping to conclusions, it is important to consider what we know and what we do not know about antipsychotic prescribing to young people."

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Stress Impairs Thinking Via Mania-Linked Enzyme

An errant enzyme linked to bipolar disorder, in the brain’s prefrontal cortex, impairs cognition under stress, an animal study shows. The disturbed thinking, impaired judgment, impulsivity, and distractibility seen in mania, a destructive phase of bipolar disorder, may be traceable to overactivity of protein kinase C (PKC), suggests the study, funded by the National Institutes of Health’s (NIH) National Institute of Mental Health (NIMH) and National Institute on Aging (NIA), and the Stanley Foundation. It explains how even mild stress can worsen cognitive symptoms, as occurs in bipolar disorder, which affects 2 million Americans.

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Movement Side Effects and Antipsychotics: Parkinsonism, Tardive Dyskinesia, and Akathesia

Antipsychotic medications in the neuroleptic group (including Abilify, Clozaril, Geodon, Haldol, Risperdal, Seroquel, Thorazine, and Zyprexa) are often used to treat symptoms such as psychosis and severe aggression that may occur in patients with a variety of psychiatric conditions including bipolar disorder. Children taking these medications must be regularly monitored for development of side effects that appear in the face and body and how the child walks (gait). These include Parkinsonism, tardive dyskinesia, and akathesia. Parents may notice these side effects in their children. If so, the child's doctor should be notified immediately.

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